Per head coach Kyle Shanahan, San Francisco 49ers running back Isaac Guerendo (knee, ankle) has likely picked up an MCL ...

Kyler Murray threw for 242 yards and four touchdowns, two to Greg Dortch, and the Arizona Cardinals beat the injury-depleted ...

George Kittle and Kyle Juszczyk said after the Sunday's season-ending loss to Arizona that they hope their futures remain in ...

Watch highlights from Week 18 matchup between the San Francisco 49ers and the Arizona Cardinals during the 2024 ...

The San Francisco 49ers concluded their 2024 season on the road against the Arizona Cardinals. Among the long list of of injured players not suiting up for the season finale was QB1 Brock Purdy, who ...

Murray’s blooming connection with Harrison and tight end Trey McBride gives the Cards something to look forward to next fall, ...

Elsewhere Baker Mayfield starred as the Tampa Bay Buccaneers beat the New Orleans Saints to win the NFC South division title ahead of the Atlanta Falcons, with Mike Evans tying Jerry Rices NFL record ...

Baker Mayfield used his legs and arm to help the Tampa Bay Buccaneers clinch their fourth straight NFC South title.

Can the Niners turn 2024 into a repeat of 2020 — a one-year, injury-filled blip? The next seven months will decide.

Claire Kittle has been a fit star for the San Francisco 49ers WAGs all season, but husband George Kittle got in on the action on Sunday.

Baker Mayfield used his legs and arm to help the Tampa Bay Buccaneers clinch their fourth straight NFC South title while putting Mike Evans over 1,000 yards receiving.