The San Francisco 49ers’ Week 15 injury report inspired a little bit of optimism on the health front as they enter a virtual ...

Head coach Kyle Shanahan on Tuesday told reporters in a pre-practice press conference that rookie running back Isaac Guerendo ...

With Christian McCaffrey and Jordan Mason on injured reserve, Guerendo made his first NFL start against the Bears. If he ...

NFL Week 15 odds, picks, predictions, TV channel, streaming for Thursday Night Football game between Los Angeles Rams and San ...

San Francisco needed to play together, and they finally did against Chicago, setting up a must-win matchup against the Rams.

With Bosa, Fred Warner, and Deommodore Lenoir all locked in on long-term deals, the 49ers are likely to lose some of their ...

The San Francisco 49ers have officially released updates on offensive tackle Trent Williams and defensive lineman Nick Bosa.

In Week 14, the Chicago Bears travel to San Fransisco to take on the 49ers. Check out the latest odds and player news.

The bad news keeps coming for the San Francisco 49ers. After a win over the Chicago Bears last week, the vibe was on an upward trajectory.

The Chicago Bears (4-8) released their final injury report ahead of Sunday's Week 14 game against the San Francisco 49ers ...

Isaac Guerendo's status for Thursday's game is "up in the air" after suffering a foot sprain in a win vs. the Bears.