The San Francisco 49ers will celebrate their initiatives to promote social justice throughout the Bay Area in their Week 15 contest against the Los Angeles Rams. Take a look at the impact the team has ...

Derrick Feldt, a 49ers fan who has beaten cancer twice, caught the attention of San Francisco star Christian McCaffrey before the Week 13 game in Buffalo and received a special gift.

At this point the past two seasons, the San Francisco 49ers were fighting for playoff positioning rather than their playoff lives.

Make room for a two-time MVP and the King. Lamar Jackson and Derrick Henry are joining the Madden 99 club, EA Sports ...

Thursday, 8:15 p.m. EST, Amazon Prime Video BetMGM NFL odds: 49ers by 2 1/2. Against the spread: Rams 6-7; 49ers 5-8. Series ...

San Francisco 49ers tight end George Kittle is one of six players nominated for the FedEx Air & Ground Player of Week 14 ...

Including the playoff game, Shanahan’s 49ers have beaten McVay’s Rams in 10 of 16 games. The two worked together for a year ...