Pittsburgh Steelers wide receiver George Pickens will almost certainly not play against the Philadelphia Eagles on Sunday, but he might be out beyond that. Pickens has a grade 2 hamstring strain that held him out of Sunday’s game against the Cleveland Browns and seems poised to force him to miss another game.

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In Week 15, the Eagles faced off against one of the worst rushing defenses in the NFL, and their best player, Saquon Barkley, ran the ball 20 times for 124 yards and a 6.2 yards-per-rush average.