The South Plains is a region in northwest Texas, United States, consisting of 24 counties. The northernmost four also form part of the Texas Panhandle region. The region consists of a portion of the Texas side of the geographical Llano Estacado and the western portion of the lower part of the Southwestern Tablelands ecological region. South Plains extend…The South Plains is a region in northwest Texas, United States, consisting of 24 counties. The northernmost four also form part of the Texas Panhandle region. The region consists of a portion of the Texas side of the geographical Llano Estacado and the western portion of the lower part of the Southwestern Tablelands ecological region. South Plains extends south of the Texas Panhandle, centered at Lubbock.